Akademik Veri Yönetim Sistemi
Combinatorial Chemistry and High Throughput Screening, cilt.24, sa.10, ss.1679-1687, 2021 (SCI-Expanded)
© 2021 Bentham Science Publishers.Background: Propolis is a natural resinous material produced by honeybees. The biological activity and phenolic profile of propolis were largely studied all over the world. However, only a few investigations have been carried out on Algerian and Turkish propolis. The aim of the present study was to compare the phenolic content, antioxidant, and antibacterial activity of propolis samples collected from different localities of Algeria and Turkey. Methods: Propolis extracts were performed using maceration in ethanol 80%. Total phenolic and flavonoid contents were determined. Antioxidant and antibacterial activities were evaluated using FRAP assay and the MIC was determined against four bacterial strains (S. aureus ATCC 25923, E. coli ATCC 25922, P. aeruginosa ATCC 27853 and K. pneumonia). Results: TP varied from 19.51 ± 0.86 to 219.66 ± 1.23 mg GAE/g. Whereas, TF varied from 5.27± 0.07 to 74.57 ± 1.03 QE/g. All samples showed good ferric reducing antioxidant power ranging from 267.30 ± 4.77 to 2387.30 ± 44.15 µmol Trolox eq./g. All Algerian propolis samples displayed a more pronounced activity against S. aureus ATCC 25923 with MIC values ranging from 0,04 ± 0.00 mg/mL to 0.30±0.06 mg/Ml, with an activity 30 times more powerful than Anatolian propolis. While, Anatolian propolis samples were most active against P. aeruginosa ATCC 27853 with MIC values ranging from 0.20±0.00 mg/mL to 0.60±0.00 mg/Ml, with an activity 5 to 10 times more powerful than Algerian propolis. Conclusion: Algerian and Anatolian propolis possessed considerable phenolic and flavonoids contents. In addition, they exhibited interesting antioxidant and antibacterial activities. Our findings suggest that both propolis could be useful in the food and pharmaceutical industries.