Why are ionic liquids so unique? – A review on ionic liquids and hemoglobin modified electrodes as electrochemical sensing platforms

SİLAH H., KUL D., USLU B.

Electrochimica Acta, cilt.532, 2025 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 532
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1016/j.electacta.2025.146504
  • Dergi Adı: Electrochimica Acta
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, INSPEC, Metadex, Civil Engineering Abstracts
  • Anahtar Kelimeler: Electrochemical sensor, Hemoglobin, Hydrogen peroxide, Ionic liquid, Nitrite, Trichloroacetic acid
  • Bilecik Şeyh Edebali Üniversitesi Adresli: Evet

Özet

Ionic liquids obtained with different properties by synthesizing with different cations and anions are widely used in many areas due to their superior properties and advantages. Ionic liquids, which increase the effective surface area, stability, and electrical conductivity of the electrode surface, can be modified with other substances, and thus more selective and sensitive electrochemical (bio)sensor platforms can be prepared. In recent years, many studies have been published in which various modified electrodes were prepared by combining ionic liquids with hemoglobin and used in the determination of some analytes. It was observed that biosensors prepared with hemoglobin and ionic liquids had good bioelectrocatalytic activity and biocompatibility, and most importantly, they accelerated the electron transfer on the electrode surface. This review summarizes the recent developments in this field by evaluating various electrode platforms modified with hemoglobin and ionic liquids developed in 58 research articles published from 2007 to the present, the target analytes analyzed with them, namely acrylamide, bromate, hydrogen peroxide, methyl parathion, nitrite, nitromethane, O2, and trichloroacetic acid, in terms of the electrochemical method used, linearity range, detection limit, interferences, and applications.