Due to its nature the stock markets can be affected by many factors. The factors are different from each other and every single one of them has its own effects. Moreover, they are different from one situation to another, but generally they are considered to be natural reasons, political issues or economical reasons. Inflation as one of the macroeconomic variables is one of the factors that many researchers and policymakers have studied and determined its impacts on stock markets. Because it can directly impact the stock market indices and the investors in the market. Many investors may lose their rationality in decision making when inflation happens. Furthermore, it causes uncertainty in the market. In that context, this paper aims to investigate the impacts of inflation rate on stock market indices in Turkey. For that purpose, we throwed light on the BIST-100 index as a representative for stock indices traded in ISE and CPI index is representing inflation rate in the same country. The study is depending on monthly published data by central bank of Turkey from which starts from January 2009 and ends with March 2020. The VAR model and Granger Causality test is applied to analyze the collected data. According to the results, it is found that there is only a one-way causality relationship between inflation and BIST-100. On the other hand, the results of impulse responses provided no meaning for relationship between the variables. Furthermore, according to variance decomposition both of the variables were contained dynamics with themselves.