Evaluation of in vitro antibiotic sensitivity of enterococci isolated from urine samples İdrar örneklerinden i̇zole edilen enterokokların in vitro antibiyotik direnç oranlarının deǧerlendirilmesi


Kalayci Ö., Yurtsever S. G., GÜNGÖR S., Uzun B., Kurultay N.

Klimik Dergisi, vol.24, no.2, pp.105-107, 2011 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 2
  • Publication Date: 2011
  • Doi Number: 10.5152/kd.2011.25
  • Journal Name: Klimik Dergisi
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.105-107
  • Keywords: Aminoglycoside resistance, Antibiotic susceptibility test, Culture, Enterococcus
  • Bilecik Şeyh Edebali University Affiliated: No

Abstract

Objective: The aim of this study is evaluation of in vitro sensitivity and resistance rate of 293 enterococcal strains isolated from the urine samples of patients with a history suggestive of urinary tract infection in our hospital. Methods: Identification was performed by conventional methods. Antimicrobial susceptibility was determined by disk diffusion method in accordance with Clinical Laboratory Standards Institute (CLSI). Results: Resistance rates of enterococcal strains to penicillin, ampicillin, erythromycin, tetracycline, levofloxacin, and ciprofloxacin were found to be 85.4% (135/158), 35.2% (92/261), 69.6% (155/223), 28.4% (35/123), 28.6% (36/126), 53.1% (110/207), respectively. A high level resistance rate was found against aminoglycosides, namely 51.2% (139/271) for gentamicin (120 mg) and 60.6% (89/147) for streptomycin (300 mg). Conclusions: Although no enterococcal strain with glycopeptide resistance was isolated, special attention should be paid to high-level aminoglycoside resistance in treating enterococcal infections.