Synthesis, crystal structure, spectral and thermal characterization, and antimicrobial activity of [Cu(HOr)(aepy)(H2O)] · H 2O (aepy = 2-aminoethylpyridine, HOr2- = orotate)

YEŞİLEL O. Z., Dege N., DARCAN C., Büyükgüngör O.

Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, cilt.62, sa.12, ss.1590-1594, 2007 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 12
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1515/znb-2007-1219
  • Dergi Adı: Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1590-1594
  • Anahtar Kelimeler: 2-aminoethylpyridine, Antimicrobial activity, Orotate complex, Vitamin B13
  • Bilecik Şeyh Edebali Üniversitesi Adresli: Evet

Özet

The copper(II) orotate complex with 2-aminoethylpyridine, [Cu(HOr)(aepy)(H2O)] · H2O, was synthesized and characterized by means of elemental and thermal analysis, magnetic susceptibility, IR and UV/vis spectroscopic, single crystal X-ray diffraction, and antimicrobial activity studies. The complex crystallizes in the triclinic system, space group F1̄, and the Cu(II) ion is five-coordinate with a distorted square-pyramidal coordination geometry. The aepy ligand and the orotate dianion behave as bidentate (N,N′ and N,Oacid) chelating ligands. The crystal structure is stabilized by intermolecular O-H·O and N-H·O hydrogen bonds, and the orotate ligand exhibits a double hydrogenbonding functionality. The new compound was found active against some gram (+)/(-) bacteria and yeast Candida albicans ATCC 10231, but there was no activity on Aspergillus niger. © 2007 Verlag der Zeitschrift für Naturforschung.