Nanomechanical characterization of electrospun biodegradable vascular scaffolds

Yilmaz E. B., Eğri S., Eğri Ö., ÇAĞLAYAN M. O.

Chemical Papers, vol.74, no.10, pp.3467-3474, 2020 (SCI-Expanded, Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 74 Issue: 10
  • Publication Date: 2020
  • Doi Number: 10.1007/s11696-020-01183-5
  • Journal Name: Chemical Papers
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core
  • Page Numbers: pp.3467-3474
  • Keywords: Compressive elastic modulus, Electrospun nanofiber, Nanoindentation, Vascular scaffolds
  • Bilecik Şeyh Edebali University Affiliated: Yes

Abstract

© 2020, Institute of Chemistry, Slovak Academy of Sciences.We proposed a method to determine the mechanical properties of electrospun nanofibers intended for use in vascular tissue engineering. Mechanical properties of poly(l-lactide) and poly(ε-caprolactone) copolymers and blends which are in fiber form were tested using the nanoindentation technique. Individual nanofibers were prone to give overweighed distributions in terms of E moduli in indentation testing. An increased compressive elastic modulus of 17 MPa was obtained in case of an increasing amount of poly(ε-caprolactone) in the fibers. It has also been found that the Hertzian model of compression is not adequate to model the elastic deformation of individual fibers.