Nanomechanical characterization of electrospun biodegradable vascular scaffolds

Yilmaz E. B., Eğri S., Eğri Ö., ÇAĞLAYAN M. O.

Chemical Papers, cilt.74, sa.10, ss.3467-3474, 2020 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 74 Sayı: 10
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1007/s11696-020-01183-5
  • Dergi Adı: Chemical Papers
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core
  • Sayfa Sayıları: ss.3467-3474
  • Anahtar Kelimeler: Compressive elastic modulus, Electrospun nanofiber, Nanoindentation, Vascular scaffolds
  • Bilecik Şeyh Edebali Üniversitesi Adresli: Evet

Özet

© 2020, Institute of Chemistry, Slovak Academy of Sciences.We proposed a method to determine the mechanical properties of electrospun nanofibers intended for use in vascular tissue engineering. Mechanical properties of poly(l-lactide) and poly(ε-caprolactone) copolymers and blends which are in fiber form were tested using the nanoindentation technique. Individual nanofibers were prone to give overweighed distributions in terms of E moduli in indentation testing. An increased compressive elastic modulus of 17 MPa was obtained in case of an increasing amount of poly(ε-caprolactone) in the fibers. It has also been found that the Hertzian model of compression is not adequate to model the elastic deformation of individual fibers.