Atıf İçin Kopyala
AKALIN ÇİFTÇİ G., ALTINTOP M. D., TEMEL H. E., ÖZDEMİR A., KAPLANCIKLI Z. A.
LETTERS IN DRUG DESIGN & DISCOVERY, cilt.14, sa.5, ss.554-566, 2017 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
14
Sayı:
5
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Basım Tarihi:
2017
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Doi Numarası:
10.2174/1570180813666160907170553
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Dergi Adı:
LETTERS IN DRUG DESIGN & DISCOVERY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.554-566
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Anahtar Kelimeler:
Thiazole, imidazole, triazole, cancer, DNA synthesis, apoptosis, mitochondrial membrane potential, acetylcholinesterase, butyrylcholinesterase, ANTIPROLIFERATIVE ACTIVITY, BIOLOGICAL EVALUATION, ANTICANCER, ACETYLCHOLINESTERASE, DESIGN, RESISTANCE, CARCINOMA, ANALOGS
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Bilecik Şeyh Edebali Üniversitesi Adresli:
Hayır
Özet
Background: Cancer is one of the leading causes of morbidity and mortality worldwide and extensive efforts have been devoted to the discovery of new anticancer agents. In the last few decades, the clinical efficacy of tiazofurin and its analogues, dasatinib and bleomycins has pointed out the importance of thiazole moiety in the field of cancer treatment.